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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Bovine immunodeficiency virus ： ウィキペディア英語版 Bovine immunodeficiency virus Bovine immunodeficiency virus (BIV) is a retrovirus belonging to the ''Lentivirus'' genus. It is similar to the ''human immunodeficiency virus'' (HIV) and infects cattle. The cells primarily infected are lymphocytes and monocytes/macrophages. ==Discovery== BIV was discovered in the late 1960s in the search for the infectious agent causing bovine leukemia/lymphosarcoma. This search led to the isolation and identification of three distinct classes of bovine retroviruses. BIV was specifically identified by Dr. Cameron Seger, a veterinarian of the Louisiana State University Agricultural Center, while he was studying dairy cattle at the Southeast Louisiana Experiment Station at Franklinton, Louisiana. The cows presented with high white blood cell counts, referred to as persistent lymphocytosis (PL) which is associated with the development of bovine leukemia/lymphosarcoma. The first animal studied was an eight-year-old Holstein cow (R-29), her white blood cell count was elevated and her physical condition was steadily declining; after delivering a calf she weakened and became severely emaciated. She had to be euthanized and necropsy was performed. The diagnosis was lymphosarcoma, however, none of the tumors usually associated with the diseases were present in the postmortem gross examination. Tissue samples were sent to Dr. Van Der Maaten at the National Animal Disease Center; Dr. Van Der Maaten was able to isolate the BIV. When the isolated BIV was inoculated into colostrum deprived young calves, they developed elevated leukocyte counts. The lymphocytosis persisted for several months and lymphadenopathy was apparent in the subcutaneous lymph nodes. This was similar to cow R-29. These calves, however, did not decline as R-29 did, which led researchers to believe that the isolated BIV was not the causative agent of the bovine leukemia/lymphosarcoma. It was put into storage and went unstudied until the discovery that acquired immunodeficiency syndrome (AIDS) was caused by HIV. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Bovine immunodeficiency virus」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.